Chlorophylline, inozivikanwawo se chlorogiline hydrochloride uye goldidene, inonzi bisbenzylisoquinoline alkaloid yakatorwa kubva murhizomes kana mapeji ezvirimwa zveChrysanthemum., ivhu haribvumidzwe, kamba yegoridhe inorembera inoparadzirwa zvakanyanya kumaruwa uye inomera yakajairika.
Iyo yakajairika mbishi zvinhu zvechinyakare Chinese mushonga, ine anti-kuzvimba uye antioxidant mhedzisiro.Inotsanangurwa mu “Supplement to Materia Medica” kuti inogona kushandiswa kurapa korera, kukosora, pfari nezvimwe zvirwere.Zvinoenderana neruzivo rweHuayuan.com, iyo kemikari formula ndeye C37H38N2O6, uye huremu hwemamorekuru i606.707.Iyo inowanzovapo muchimiro cheyero kana chiedza chepfu yeroti, iyo iri nyore kuve oxidized uye isiri nyore kuora.Inonyungudika zviri nyore mune mamwe organic solvents, senge ether neacetone, inonyungudika nyore muacidic aqueous solution, uye isinganyunguriki mupetroleum ether.
Musi waChivabvu 10, 2022, apo denda idzva rekorona rakanga richipisa, nhau huru nezve fenugreek yakaonekwa.Masayendisiti echiChinese akawana kodzero dzekugadzira patent yemishonga mitsva yekurapa korona itsva.Iyo yekuwedzeredza yekurambidza kudzokororwa kwekoronavirus inguva 15,393.Sezvinoratidzwa nezita racho, fenugreek inogona kumisa kugona kudzokorodza kweiyo coronavirus nyowani ine yakanyanya kudhura kuita.Tichifunga kuti huwandu hwehutachiona hwepakutanga huri 15,393, zvino kana uchishandisa 10 micromol / litre ye fenugreek Mushure mokunge mumiririri agadziriswa, hutachiona humwe chete hunoramba huripo pakupedzisira.Pepa rakaburitswa nenyanzvi dzeAmerica mujenari "Sainzi" rakasimbisawo iyi data, uye kuyedza kwakadzokororwa.
Naizvozvo, pamusoro pechinyakare kurapwa kwemhasuru uye kukuvara kweitsvo, adjuvant kurapwa kwegomarara rezamu, inhibition yeHIV-1 uye zvimwe zvinoshandiswa, fenugreek inogona kuve nesimba guru mukurwisa denda idzva rekorona.Tsvagiridzo zhinji dzakavakirwa pafenugreek dzinofanirwa kumisa boom, saka, pamusoro pekutenga mhando hombe dzefenugreek reagents muHuayuan Mall, nezvimwewo, vaongorori vesainzi vanogonawo kuburitsa nekuzvigadzirira ivo vega.Heino nzira yekugadzirira fenugreek:
1. Tora 1 kg yehupfu hwemidzi, unyorove ne 0.6 malita e5% sodium carbonate solution, uye uisiye kwemaawa maviri kusvikira yaoma kuti uone kuti poda yemidzi inogona kunyatsotora lye.
2. Inyika midzi yakaomeswa poda mu1.5L benzene, woisiya kwemazuva matatu, wozosefa kuti uwane yasara, wonyika mubenzene kwemamwe mazuva maviri, sefa zvakare wobva wanyura kamwe chete nechiyero chimwe chete chebenzene, wobva wainyudza. sefa katatu.The benzene liquid yakabatanidzwa ichibva yavharwa.
3. Bvisa mvura yebenzene mudanho rechipiri ine 10% hydrochloric acid kusvikira mvura yebenzene isisina alkaloids.Izvo zvinofanirwa kucherechedzwa kuti huwandu hukuru hwe nyore emulsifiable chena porridge ichave yakawedzera panguva yekuita.
4. Alkalize the acid solution munhanho 3 ine saturated sodium carbonate solution,
5. Shandisa chloroform kuburitsa alkaline solution kanokwana kana, uye sanganisa yakabviswa chloroform solution.
6. Pukuta mushonga wechloroform neanhydrous sodium sulfate, dzorera chloroform ne distillation, uye panguva imwe chete wana 17.5g yepale yellow foamy alkaloids.
7. Dissolve the foamy alkaloid mu 35 ml yeacetone, uye uisiye kwemaawa maviri, makristasi machena etsono anonaya.Mushure mokusefa makristasi, geza kamwe chete neacetone shoma uye wooma kuti uwane 1.8 g ye phyllophylline.
8. Isa 2.5 ml yebenzene kudoro raamai acetone mudanho rechinomwe, worisiya husiku hwose.Pachave necolumnari makristasi anonaya.Mushure mekusefa makristasi, geza kamwe chete neacetone uye wooma, iyo inokosha 6.8 gramu yefenugreek benzene adduct.
9. Dissolve the fenugreek benzene adduct in chloroform, pfuura nepakati pealumina chromatography column, uye alumina dosage inenge 20.4 gramu (reshiyo yealkaloid nealuminium i1: 3), uye mvura inowanikwa mushure mekuiswa kwesefa nekuomeswa.Iyo yakachenuruka yehupfu hupfu inogona kuwanikwa, kureva, fenugreek.
Nguva yekutumira: Jul-08-2022